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Diagnostic accuracy of three commercially available one step RT-PCR assays for the detection of SARS-CoV-2 in resource limited settings.

Abay SisayAdugna Abera HirpaBoja DuferaTujuba EndriasGeremew TasewAbraham TesfayeSonja HartnackDereje BeyeneAdey Feleke Desta
Published in: PloS one (2022)
While all the three RT-PCR assays displayed comparable sensitivities, the specificities of TIB MOLBIOL and Da An were considerably higher than BGI. These results help adjust the apparent prevalence determined by the three RT-PCRs and thus support public health decisions in resource limited settings and consider alternatives as per their prioritization matrix.
Keyphrases
  • public health
  • sars cov
  • real time pcr
  • high throughput
  • risk factors
  • respiratory syndrome coronavirus
  • magnetic resonance imaging
  • coronavirus disease
  • label free
  • single cell