Diagnostic accuracy of three commercially available one step RT-PCR assays for the detection of SARS-CoV-2 in resource limited settings.
Abay SisayAdugna Abera HirpaBoja DuferaTujuba EndriasGeremew TasewAbraham TesfayeSonja HartnackDereje BeyeneAdey Feleke DestaPublished in: PloS one (2022)
While all the three RT-PCR assays displayed comparable sensitivities, the specificities of TIB MOLBIOL and Da An were considerably higher than BGI. These results help adjust the apparent prevalence determined by the three RT-PCRs and thus support public health decisions in resource limited settings and consider alternatives as per their prioritization matrix.