WiNTRLINC1/ASCL2/c-Myc Axis Characteristics of Colon Cancer with Differentiated Histology at Young Onset and Essential for Cell Viability.

Kazuko YokotaYoko TanakaHiroki HaradaTakeshi KaidaSyuji NakamotoTakafumi SoenoYoshiki FujiyamaMitsuo YokotaKen KojoHirohisa MiuraTakahiro YamanashiTakeo SatoTakatoshi NakamuraMasahiko WatanabeKeishi Yamashita

Published in: Annals of surgical oncology (2019)

The enhanced WiNTRLINC1/ASCL2/c-Myc axis involved in Wnt pathway activation is a common pathway essential for differentiated colon tumorigenesis, especially with young onset, and may be essential for a viable phenotype of colon cancer.

Keyphrases

middle aged
stem cells
cell proliferation