Anxiety, depression, and inflammation after restorative proctocolectomy.
Venkata Subhash GorrepatiSanjay YadavAugust StuartWalter KoltunEvangelos MessarisEmmanuelle D WilliamsMatthew D CoatesPublished in: International journal of colorectal disease (2018)
Anxiety and depression were more common in patients experiencing inflammatory conditions of the pouch. UC without pouchitis and FAP patients demonstrated lower rates of A&D (that were comparable to the general population), implying that having an IPAA alone was not enough to increase risk for A&D. Factors independently associated with A&D in IPAA included an inflamed pouch, corticosteroid use, smoking, and female gender.