Carboxylesterase 1-Based Drug-Drug Interaction Potential of Remimazolam: In-Vitro Studies and Literature Review.

Karl-Uwe PetersenWolfgang SchmalixMarija PesicThomas Stöhr

Published in: Current drug metabolism (2024)

Data and analyses suggest a very low potential of remimazolam for pharmacokinetic DDIs mediated by CES1. The theoretical approach and compiled data are not specific to remimazolam and, hence, applicable in the evaluation of other CES1 substrates.

Keyphrases

electronic health record
big data
case report
adverse drug
human health
drug induced