Novel combination immunotherapy for pancreatic cancer: potent anti-tumor effects with CD40 agonist and interleukin-15 treatment.

Jonas R M Van AudenaerdeElly MarcqBianca von ScheidtAshleigh S DaveyAmanda J OliverJorrit De WaeleDelphine QuatannensJinthe Van LoenhoutPatrick PauwelsGeert RoeyenFilip LardonClare Y SlaneyMarc PeetersMichael H KershawPhillip K DarcyEvelien Ljm Smits

Published in: Clinical & translational immunology (2020)

These novel preclinical data support initiation of a first-in-human clinical trial with this combination immunotherapy strategy in pancreatic cancer.

Keyphrases

clinical trial
endothelial cells
electronic health record
study protocol
phase ii
double blind
cell therapy
anti inflammatory
replacement therapy
nk cells
phase iii
data analysis