Ventilation heterogeneity and oscillometry predict asthma control improvement following step-up inhaled therapy in uncontrolled asthma.

Francesca S M TangSandra RuttingCatherine E FarrowKatrina O TongaJoanna WattsJessica R Dame-CarrolAmy BertolinGregory G KingCindy ThamrinDavid G Chapman

Published in: Respirology (Carlton, Vic.) (2020)

Step-up to high-dose combination treatment in uncontrolled asthma is associated with improved peripheral airway function as measured by Xrs5Hz and MBNW. Baseline MBNW and FOT parameters correlated with the improvement in symptoms and may predict a positive response to up-titration in uncontrolled asthmatic patients.

Keyphrases

lung function
chronic obstructive pulmonary disease
high dose
cystic fibrosis
allergic rhinitis
end stage renal disease
newly diagnosed
ejection fraction
prognostic factors
low dose
air pollution
single cell
patient reported outcomes
mesenchymal stem cells
sleep quality
replacement therapy
patient reported