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Dynamic Responsive Inguinal Scaffold Activates Myogenic Growth Factors Finalizing the Regeneration of the Herniated Groin.

Giuseppe AmatoGiorgio RomanoVito RodolicoRoberto PuleioPietro Giorgio CalòGiuseppe Di BuonoLuca CiceroGiorgio RomanoThorsten Oliver GoetzeAntonino Agrusa
Published in: Journal of functional biomaterials (2022)
The investigation appears to confirm that a 3D polypropylene scaffold designed to confer dynamic responsivity, unlike the fibrotic scar plate of static meshes, attracts myogenic growth factors turning the biological response into tissue regeneration. Newly developed muscles allow the scaffold to restore the integrity of the inguinal barrier.
Keyphrases
  • tissue engineering
  • stem cells
  • skeletal muscle
  • wound healing
  • radical prostatectomy
  • systemic sclerosis
  • cancer therapy
  • drug delivery