Login / Signup

Baghdadite: A Novel and Promising Calcium Silicate in Regenerative Dentistry and Medicine.

Gamal Abdel Nasser AtiaHasi Rani BaraiHany K ShalabyNaema Goda AliShaimaa Mohammed MorsyMohamed Mohamady GhobashyHager Abdel Nasser AttiaSang Woo Joo
Published in: ACS omega (2022)
For several years, ceramic biomaterials have been extensively utilized to rebuild and substitute for body tissues. Calcium silicates have been proven to exhibit excellent bioactivity due to apatite formation and cell proliferation stimulation, in addition to degradability at levels adequate for hard tissue formation. These ceramics' excellent biological characteristics have attracted researchers. Baghdadite is a calcium silicate incorporating zirconium ions that enhances human osteoblast multiplication and development, increasing mineralization, and ossification. It has currently received much interest in academic institutions and has been extensively explored in the form of permeable frameworks, varnishes, bone adhesive and gap fillings, microparticles, and nanospheres, particularly in a wide range of biomedical applications. This review article aims to summarize and analyze the most recent research on baghdadite's mechanical characteristics, apatite-forming capability, dissolution pattern, and physiochemical qualities as a scaffold for dentofacial tissuè regeneration purposes.
Keyphrases
  • stem cells
  • cell proliferation
  • tissue engineering
  • multidrug resistant
  • bone regeneration
  • endothelial cells
  • mesenchymal stem cells
  • gene expression
  • quantum dots
  • cell cycle
  • induced pluripotent stem cells