SIRT6 Improves Hippocampal Neurogenesis Following Prolonged Sleep Deprivation Through Modulating Energy Metabolism in Developing rats.

Junke JiaWanjiang TaoTing ChenQi ZhongJiahui SunYutong XuXiaokai SuiZongze ZhangZongze Zhang

Published in: Molecular neurobiology (2023)

Our results suggest that SIRT6 plays a critical role in maintaining energy metabolism homeostasis in the hippocampus after sleep deprivation, promoting hippocampal neurogenesis and enhancing memory during development.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
blood brain barrier
brain injury
sleep quality
oxidative stress
physical activity
ischemia reperfusion injury
working memory
signaling pathway
temporal lobe epilepsy
depressive symptoms