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Evaluation and Comparison of the Effects of Mature Silkworm ( Bombyx mori ) and Silkworm Pupae Extracts on Schwann Cell Proliferation and Axon Growth: An In Vitro Study.

Mohammad Hossein KhosropanahMasoumeh Majidi ZolbinAbdol-Mohammad KajbafzadehLeili AmaniIsmaeil HarririanAshkan AzimzadehTouraj NejatianMahdi Alizadeh VaghaslooZahra Hassannejad
Published in: Iranian journal of pharmaceutical research : IJPR (2023)
The findings of this study demonstrated that extracts obtained from silkworms, especially pupae, can play an effective role in Schwann cell proliferation and axonal growth, which can be strong evidence for nerve regeneration, and, consequently, repairing peripheral nerve damage.
Keyphrases
  • peripheral nerve
  • cell proliferation
  • cell cycle
  • stem cells
  • spinal cord injury
  • oxidative stress
  • pi k akt
  • optic nerve
  • signaling pathway