Impact of Thyroid Cancer Treatment on Renal Function: A Relevant Issue to Be Addressed.
Rossella Di PaolaAnanya DeAnna CapassoSofia GiulianaRoberta RanieriCarolina RuosiAntonella SciarraCaterina VitaglianoAlessandra Fortunata PernaGiovambattista CapassoMariadelina SimeoniPublished in: Journal of personalized medicine (2023)
Thyroid cancers require complex and heterogeneous therapies with different impacts on renal function. In our systematic literature review, we analyzed several aspects: renal function assessment, the impact of radiotherapy and thyroid surgery on kidney functioning, and mechanisms of nephrotoxicity of different chemotherapy, targeted and immunologic drugs. Our study revealed that the renal impact of thyroid cancer therapy can be a limiting factor in all radiotherapy, surgery, and pharmacological approaches. It is advisable to conduct a careful nephrological follow-up imposing the application of body surface based estimated Glomerular Filtration Rate (eGFR) formulas for the purpose of an early diagnosis and treatment of renal failure, guaranteeing the therapy continuation to thyroid cancer patients.
Keyphrases
- cancer therapy
- minimally invasive
- locally advanced
- coronary artery bypass
- early stage
- small cell lung cancer
- drug delivery
- radiation therapy
- radiation induced
- case report
- surgical site infection
- percutaneous coronary intervention
- acute coronary syndrome
- stem cells
- tyrosine kinase
- squamous cell carcinoma
- coronary artery disease
- drug induced
- chemotherapy induced