Detection of clinically relevant early genomic lesions in B-cell malignancies from circulating tumour DNA using a single hybridisation-based next generation sequencing assay.

Piers A BlomberyGeorgina L RylandJohn MarkhamJerick GuintoMeaghan WallMichelle McBeanKate JonesElla R ThompsonDaniel L CameronAnthony T PapenfussMiles H PrinceMichael DickinsonDavid Alan Westerman

Published in: British journal of haematology (2017)

Keyphrases

circulating tumor
copy number
cell free
circulating tumor cells
high throughput
loop mediated isothermal amplification
single molecule
label free
real time pcr
genome wide
gene expression
nucleic acid