Tranexamic acid administration during total joint arthroplasty surgery is not associated with an increased risk of perioperative seizures: a national database analysis.

Meghan A KirkseyLauren A WilsonMegan FiasconaroJashvant PoeranJiabin LiuStavros G Memtsoudis

Published in: Regional anesthesia and pain medicine (2020)

Despite increasing TXA utilization in total joint arthroplasty, we found an overall low seizure incidence. TXA use was not associated with elevated odds of perioperative seizure, even in patients with history of seizure.

Keyphrases

temporal lobe epilepsy
cardiac surgery
patients undergoing
minimally invasive
coronary artery bypass
risk factors
quality improvement
emergency department
acute kidney injury
surgical site infection
acute coronary syndrome
data analysis
drug induced