Hyperoxia does not affect oxygen delivery in healthy volunteers while causing a decrease in sublingual perfusion.
Bob SmitYvo M SmuldersEtto C EringaHarry P M M GelissenArmand R J GirbesHarm-Jan S de GroothHans H M SchotmanPeter G SchefferHeleen M Oudemans-van StraatenAngelique M E Spoelstra-de ManPublished in: Microcirculation (New York, N.Y. : 1994) (2018)
In healthy volunteers, supraphysiological arterial oxygen tensions have no effect on systemic DO2 . Sublingual microcirculatory PVD decreased in a dose-dependent fashion. All hemodynamic changes appear negligible up to an arterial oxygen tension of 20 kPa.
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