Ago2 Protects Against Diabetic Cardiomyopathy by Activating Mitochondrial Gene Translation.

Jiabing ZhanKunying JinRong XieJiahui Fan Yuyan Tang Chen Chen Huaping Li Dao-Wen Wang

Published in: Circulation (2023)

axis links glucotoxicity to cardiac electron transport chain imbalance, providing new mechanistic insights and the basis to develop mitochondria targeting therapies for diabetic cardiomyopathy.

Keyphrases

heart failure
type diabetes
wound healing
oxidative stress
left ventricular
signaling pathway
cell death
genome wide
copy number
reactive oxygen species
dna methylation
genome wide identification
solar cells