Randomised controlled trial of the short-term effects of osmotic-release oral system methylphenidate on symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorder: CIAO-II study.
Philip J AshersonLena JohanssonRachel HollandMegan BeddingAndrew ForresterLaura GiannulliYlva GinsbergSheila HowittImogen KretzschmarStephen M LawrieCraig MarshCaroline KellyMegan MansfieldClare McCaffertyKhuram KhanUlrich Müller-SedgwickJohn StrangGrace WilliamsonLauren WilsonSusan YoungSabine LandauLindsay D G ThomsonPublished in: The British journal of psychiatry : the journal of mental science (2022)
ADHD symptoms did not respond to OROS-methylphenidate in young adult prisoners. The findings do not support routine treatment with OROS-methylphenidate in this population. Further research is needed to evaluate effects of higher average dosing and adherence to treatment, multi-modal treatments and preventative interventions in the community.