Acquired mild cognitive impairment in adults with Down syndrome: Age-related prevalence derived from single point assessment data normed by degree of intellectual disability.

Chris OliverDawn AdamsAnthony J HollandStephanie S G BrownSarah BallKaren DoddJanet Carr

Published in: International journal of geriatric psychiatry (2021)

Psychometric data indicate single point assessment of AMCI is possible for the majority of adults with DS. Two peaks for age-related prevalence of AMCI suggest the risk for onset of AD conferred by trisomy of chromosome 21 is moderated by another factor, possibly ApoE status.

Keyphrases

mild cognitive impairment
intellectual disability
cognitive decline
risk factors
autism spectrum disorder
electronic health record
big data
high fat diet
data analysis
adipose tissue
artificial intelligence