Genetic determinants of childhood and adult height associated with osteosarcoma risk.

Chenan ZhangLibby M MorimotoAdam J de SmithHelen M HansenJulio Gonzalez-MayaAlyson A EndicottIvan V SmirnovCatherine MetayerWenjie JiaoWilliam C EwardJoseph L WiemelsKyle M Walsh

Published in: Cancer (2018)

A genetic propensity for taller adult and childhood height attainments contributed independently to osteosarcoma risk in the current study data. These results suggest that the biological pathways affecting normal bone growth may be involved in osteosarcoma etiology.

Keyphrases

childhood cancer
body mass index
genome wide
young adults
physical activity
data analysis
postmenopausal women
bone regeneration
breast cancer risk