Race/ethnicity and underlying disease influences hematopoietic stem/progenitor cell mobilization response: A single center experience.
Chukwuemeka UzokaLi C LiuYoungmin ParkYuankai LinPritesh PatelSally Campbell-LeeKaren SweissXinhe WangElena TepakDavid PeaceSantosh SarafDamiano RondelliNadim MahmudPublished in: Journal of clinical apheresis (2021)
Our study shows that race/ethnicity and diagnostic group differences influenced CD34+ cell mobilization response across donor types. Interestingly, autologous MM donors with the aid of plerixafor displayed comparable CD34 yields to allogeneic donors. Even though both MM and non-MM donors received plerixafor, non-MM donors had significantly lower CD34 yields among AA and O donors but not in W donors. Larger studies would be required to validate the role of diagnostic groups and race/ethnicity interactions.