Critically ill patients with COVID-19-associated acute kidney injury treated with kidney replacement therapy: Comparison between the first and second pandemic waves in São Paulo, Brazil.
Farid SamaanRafaela Andrade Penalva FreitasRenata VianaLívia GâmbaroKarlla CunhaTales Dantas VieiraValkercyo FeitosaEric Aragão CorreaAlexandre Toledo MacielSylvia AranhaEduardo Atsushi OsawaRoberta PillarElias Marcos da Silva FlatoRenata Cristina da SilvaElisa CarneiroFabrizzio Batista Guimarães de Lima SouzaPaula Regina Gan RossiMunira Bittencourt AbudHenrique Pinheiro KonigsfeldRiberto Garcia da SilvaRicardo Barbosa Cintra de SouzaSaurus Mayer CoutinhoMiguel Ângelo GoesBárbara Antunes Bruno da SilvaDirce Maria Trevisan ZanettaEmmanuel Almeida BurdmannPublished in: PloS one (2023)
In the Sao Paulo megalopolis, the lethality of critically ill patients with COVID-19-associated AKI treated with KRT was higher in the second wave of the pandemic, despite these patients being younger and having fewer comorbidities. Potential factors related to this poor outcome were difficulties in health care access, lack of intra-hospital resources, delay vaccination and virus variants.
Keyphrases
- acute kidney injury
- replacement therapy
- healthcare
- sars cov
- newly diagnosed
- coronavirus disease
- end stage renal disease
- ejection fraction
- chronic kidney disease
- cardiac surgery
- smoking cessation
- prognostic factors
- emergency department
- copy number
- peritoneal dialysis
- dna methylation
- patient reported outcomes
- climate change
- acute care