Breast-feeding regulates immune system development via transforming growth factor-β in mice pups.

Keita SakaguchiAkemi KoyanagiFumitaka KamachiAkiko HaraumaAsako ChibaKen HisataToru MoriguchiToshiaki ShimizuSachiko Miyake

Published in: Pediatrics international : official journal of the Japan Pediatric Society (2018)

Breast milk regulates the differentiation and expansion of innate and adaptive immune cells partly due to TGF-β. Hence, TGF-β in breast milk may be a new therapeutic target for innate immune system-mediated diseases of infancy.

Keyphrases

transforming growth factor
immune response
epithelial mesenchymal transition
weight gain
high fat diet induced
body mass index
adipose tissue
physical activity
wild type
weight loss