New Microbe Killers: Self-Assembled Silver(I) Coordination Polymers Driven by a Cagelike Aminophosphine.
Sabina W JarosMatti HaukkaMagdalena FlorekMaria de Fátima C Guedes da SilvaArmando J L PombeiroAlexander M KirillovPiotr SmoleńskiPublished in: Materials (Basel, Switzerland) (2019)
New Ag(I) coordination polymers, formulated as [Ag(µ-PTAH)(NO3)2]n (1) and [Ag(µ-PTA)(NO2)]n (2), were self-assembled as light- and air-stable microcrystalline solids and fully characterized by NMR and IR spectroscopy, electrospray ionization mass spectrometry (ESI-MS(±), elemental analysis, powder (PXRD) and single-crystal X-ray diffraction. Their crystal structures reveal resembling 1D metal-ligand chains that are driven by the 1,3,5-triaza-7-phospaadamantane (PTA) linkers and supported by terminal nitrate or nitrite ligands; these chains were classified within a 2C1 topological type. Additionally, the structure of 1 features a 1D→2D network extension through intermolecular hydrogen bonds, forming a two-dimensional hydrogen-bonded network with fes topology. Furthermore, both products 1 and 2 exhibit remarkable antimicrobial activity against different human pathogen bacteria (S. aureus, E. coli, and P. aeruginosa) and yeast (C. albicans), which is significantly superior to the activity of silver(I) nitrate as a reference topical antimicrobial.
Keyphrases
- high resolution
- mass spectrometry
- visible light
- nitric oxide
- quantum dots
- ms ms
- solid state
- gold nanoparticles
- candida albicans
- highly efficient
- endothelial cells
- drinking water
- liquid chromatography
- escherichia coli
- silver nanoparticles
- magnetic resonance
- staphylococcus aureus
- gas chromatography
- high performance liquid chromatography
- genome wide
- capillary electrophoresis
- gene expression
- induced pluripotent stem cells
- single cell
- single molecule
- magnetic resonance imaging
- wound healing
- tandem mass spectrometry
- solid phase extraction
- simultaneous determination
- contrast enhanced
- cell wall