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Possible correlation of sonic hedgehog signaling with epithelial-mesenchymal transition in muscle-invasive bladder cancer progression.

Koichi KitagawaKatsumi ShigemuraShian-Ying SungKuan-Chou ChenChao-Ching HuangYi-Te ChiangMing-Che LiuTzu-Wen HuangFukashi YamamichiToshiro ShirakawaMasato Fujisawa
Published in: Journal of cancer research and clinical oncology (2019)
Shh signaling and EMT were especially enhanced in muscle-invasive bladder cancer progression and invasion, and suppressed by the inhibition of Shh signaling.
Keyphrases
  • muscle invasive bladder cancer
  • epithelial mesenchymal transition
  • transforming growth factor
  • cell migration