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Task-dependent functional connectivity of pain is associated with the magnitude of placebo analgesia in pain-free individuals.

Nicholas J BushJeff BoissoneaultJanelle LetzenRoland StaudMichael E Robinson
Published in: European journal of pain (London, England) (2023)
This article provides support and insight for task-dependent functional connectivity differences related to the magnitude of placebo analgesia. Our findings provide key support that the magnitude of expectation-based placebo response depends on the coupling of regions associated with somatosensory and attentional processing.
Keyphrases
  • functional connectivity
  • pain management
  • resting state
  • chronic pain
  • postoperative pain
  • double blind
  • phase iii
  • neuropathic pain
  • ultrasound guided
  • placebo controlled
  • working memory
  • clinical trial
  • spinal cord injury