Adenylate cyclase type 9 antagonizes cAMP accumulation and regulates endothelial signaling involved in atheroprotection.
Yohann RautureauMarianne BerlatieDaniel RivasKurunradeth UyAlexandre BlanchetteGéraldine MiquelMarie-Ève HigginsMélanie MecteauAudrey NaultLouis VilleneuveVéronique LavoieGabriel Théberge-JulienGeneviève BrandLine LapointeMaxime DenisCamille RosaAnnik FortierLucie BlondeauMarie-Claude GuertinMarie-Pierre DubéÉric ThorinJonathan LedouxDavid RhaindsÉric RhéaumeJean-Claude TardifPublished in: Cardiovascular research (2022)
Adcy9 is expressed in endothelial cells and regulates local cAMP and endothelial functions including permeability relevant to atherogenesis.