Telomere shortening in late-life depression: A potential marker of depression severity.

Ana Paula Mendes-SilvaErica Leandro Marciano VieiraGabriela XavierLucelia Scarabeli Silva BarrosoLaiss BertolaEfrem Augusto Ribeiro MartinsElisa Macedo BrietzkeSintia Iole Nogueira BelangeroBreno Satler Diniz

Published in: Brain and behavior (2021)

We found that older adults with LLD have shorter telomere than healthy controls, especially those with a more severe depressive episode. Our findings suggest that shorter TL can be a marker of the severity of depressive episodes in older adults and indicate that these individuals may be at higher risk of age-associated adverse outcomes linked to depression.

Keyphrases

depressive symptoms
sleep quality
physical activity
bipolar disorder
stress induced