Fever and antibiotic use in maternal urinary tract infections during pregnancy and risk of congenital heart defects: Findings from the National Birth Defects Prevention Study.
Jenil R PatelMaria D PolitisMeredith M HowleyMarilyn L BrowneElijah Holbrook BolinElizabeth C AilesCandice Y JohnsonEverett MagannWendy N Nembhardnull nullPublished in: Birth defects research (2023)
Findings in the present study suggest that fever due to UTI and corresponding maternal antibiotic use do not substantially modify the association between maternal UTIs and specific CHDs in offspring. Further studies with larger sample sizes are warranted to guide clinical management of UTIs during the periconceptional period.