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Systematic review: the natural history of alpha-1 antitrypsin deficiency, and associated liver disease.

Sarah A TownsendR G EdgarPaul EllisD KantasPhilip Noel NewsomeA M Turner
Published in: Alimentary pharmacology & therapeutics (2018)
The clinical course of liver disease in individuals with AATD remains poorly understood, but affects about 10% of those with AATD. More research is required to identify those patients at risk of developing liver disease at an early stage, and to provide alternative treatments to liver transplantation.
Keyphrases
  • systematic review
  • early stage
  • meta analyses
  • radiation therapy