Clinical and prognostic associations of liver volume determined by computed tomography in acute liver failure.

Abigail ZabronAlberto QuagliaEvangelia FatourouPraveen PedduDylan LewisMichael HeneghanChristopher WillarsGeorg AuzingerNigel HeatonJulia WendonPauline KaneJohn KaraniWilliam Bernal

Published in: Liver international : official journal of the International Association for the Study of the Liver (2018)

In patients with ALF/ALI, LV shows marked variation by the cause of disease, and in prognostic importance. In indeterminate and DILI cases, loss of volume to <1000 cm3 may indicate irreversible liver injury and regenerative failure and serve as an early clinical predictor for the development of high-grade encephalopathy and death.

Keyphrases

liver failure
drug induced
liver injury
high grade
computed tomography
hepatitis b virus
stem cells
mesenchymal stem cells
early onset
positron emission tomography
cell therapy
intensive care unit
pet ct
acute respiratory distress syndrome