Is ibuprofen superior to indomethacin for patent ductus arteriosus in Japanese preterm infants?
Shun MatsumuraSatoshi MasutaniAyumi OshimaMasayo KanaiFumihiko NambaAkio IshiguroKazuhiko KabePublished in: Pediatrics international : official journal of the Japan Pediatric Society (2021)
Except for an increase in serum creatinine levels by >0.3 mg/dL, which was less frequent with IBU, IBU had similar efficacy and safety as IND for preterm PDA. Ibuprofen and IND should be cautiously administered.