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Is ibuprofen superior to indomethacin for patent ductus arteriosus in Japanese preterm infants?

Shun MatsumuraSatoshi MasutaniAyumi OshimaMasayo KanaiFumihiko NambaAkio IshiguroKazuhiko Kabe
Published in: Pediatrics international : official journal of the Japan Pediatric Society (2021)
Except for an increase in serum creatinine levels by >0.3 mg/dL, which was less frequent with IBU, IBU had similar efficacy and safety as IND for preterm PDA. Ibuprofen and IND should be cautiously administered.
Keyphrases
  • preterm infants
  • low birth weight
  • postoperative pain
  • preterm birth
  • uric acid