Interaction of germline variants in a family with a history of early-onset clear cell renal cell carcinoma.

Emmanuelle NicolasElena V DemidovaWaleed IqbalIlya G SerebriiskiiRamilia VlasenkovaPooja GhataliaYan ZhouKim RaineyAndrea F FormanRoland L DunbrackErica A GolemisMichael J HallMary B DalySanjeevani Arora

Published in: Molecular genetics & genomic medicine (2019)

Together, these data suggest the possibility of risk associated with interaction of two or more variants.

Keyphrases

early onset
late onset
copy number
electronic health record
dna repair
big data
gene expression
machine learning
deep learning