Body composition and mortality in men receiving prostate radiotherapy: A pooled analysis of NRG/RTOG 9406 and NRG/RTOG 0126.
Andrew M McDonaldLyudmila DeMoraEddy S YangJohn M HoyleAndrew LenzieGrant R WilliamsJeff M MichalskiDon YeeJean-Paul BaharyRobert B DenMack RoachRobert T DessMark V MishraRichard K ValicentiHarold Y LauSamuel R MarcromLuis SouhamiLucas C MendezYuhchyau ChenDesiree E DoncalsStephanie L PughFelix Y FengHoward M SandlerPublished in: Cancer (2022)
This study strongly supports that body composition is related to mortality in men with localized PCa. The inclusion of psoas area in the RPA classification tree suggests that body composition provides additive information to age and comorbidity status for mortality prediction, particularly among older men. More research is needed to determine the clinical impact of body composition on prognostic models in men with PCa.
Keyphrases
- body composition
- resistance training
- bone mineral density
- cardiovascular events
- middle aged
- risk factors
- machine learning
- deep learning
- type diabetes
- healthcare
- radiation therapy
- cardiovascular disease
- squamous cell carcinoma
- coronary artery disease
- radiation induced
- health information
- benign prostatic hyperplasia
- social media
- rectal cancer