Automated Computational Detection of Interstitial Fibrosis, Tubular Atrophy, and Glomerulosclerosis.
Brandon GinleyKuang Yu JenSeung Seok HanLuís RodriguesSanjay JainAgnes B FogoJonathan ZuckermanVighnesh WalavalkarJeffrey C MiecznikowskiYumeng WenFelicia YenDonghwan YunKyung Chul MoonAvi Z RosenbergChirag R ParikhPinaki SarderPublished in: Journal of the American Society of Nephrology : JASN (2021)
ML algorithms can be trained to replicate the IFTA and glomerulosclerosis assessment performed by renal pathologists. This suggests computational methods may be able to provide a standardized approach to evaluate the extent of chronic kidney injury in situations in which renal-pathologist time is restricted or unavailable.