Login / Signup

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition.

Nan ZhangPengyu ZhangXizhi DengMin ZhuYixin HuDongxiao JiLufan LiYang LiuWen ZengMin Ke
Published in: Investigative ophthalmology & visual science (2024)
Based on the results, NR effectively enhances intracellular levels of NAD+, thereby mitigating abnormal ECM deposition and TM dysfunction in GIG by attenuating mitochondrial damage induced by GCs. Thus, NR has promising potential as a therapeutic candidate for GIG treatment.
Keyphrases
  • extracellular matrix
  • oxidative stress
  • diabetic rats
  • drug induced
  • risk assessment
  • optic nerve
  • endothelial cells
  • cataract surgery