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Promising Drug Fondaparinux for the Treatment of COVID-19: an In Silico Analysis of Low Molecular Weight Heparin, Direct Oral Anticoagulant, and Antiplatelet Drug Interactions with Host Protease Furin.

Tugba Ertan-BolelliKayhan BolelliSıtkı Doga ElçiFatma Burcu Belen
Published in: Cardiovascular drugs and therapy (2022)
Our findings have shown that LMWHs and fondaparinux can be used for their possible antiviral effects in COVID-19 patients. Our results have shown that in accordance with heparin and LMWH, fondaparinux can also be a candidate for "drug repurposing" in COVID-19 therapy, not only because of their anticoagulant but also possible antiviral effects.
Keyphrases
  • sars cov
  • venous thromboembolism
  • coronavirus disease
  • atrial fibrillation
  • adverse drug
  • growth factor
  • drug induced
  • emergency department
  • molecular docking
  • bone marrow
  • drug discovery