Transcriptional signatures of the BCL2 family for individualized acute myeloid leukaemia treatment.
Chansub LeeSungyoung LeeEunchae ParkJunshik HongDong-Yeop ShinJa Min ByunHongseok YunYoungil KohSung Soo YoonPublished in: Genome medicine (2022)
This study proposes BFSigs as a biomarker for the effective selection of apoptosis targeting treatments and cancer pathways to co-target in AML.
Keyphrases
- acute myeloid leukemia
- papillary thyroid
- liver failure
- oxidative stress
- gene expression
- endoplasmic reticulum stress
- bone marrow
- transcription factor
- cell death
- dendritic cells
- respiratory failure
- cell cycle arrest
- squamous cell carcinoma
- intensive care unit
- cancer therapy
- drug induced
- immune response
- hepatitis b virus
- drug delivery
- lymph node metastasis
- replacement therapy