Epidemiology of Type 3 Poliovirus AFP Cases in Israel between 1973 and 1988: Whole Genome Sequencing of RNA Extracted Directly from Archived Stocks to Avoid Re-Culturing Neurovirulent Wild Poliovirus.

Lester M ShulmanMajid LaassriRachel HandsherTatiana ZagorodnyayaDanit SoferMerav WeilElla MendelsonKonstantin Chumakov

Published in: Vaccines (2022)

Whole or near-whole genome sequence information, obtained from RNA extracted directly from the archived material, safely provided detailed genetic information linked to patient data from a time when limited sequence information was previously available and revealed the pattern of transmission of wild PV3 in Israel.

Keyphrases

health information
case report
electronic health record
risk factors
genome wide
amino acid
single cell
dna methylation
gene expression
social media
machine learning
copy number
data analysis