Antibiotic treatment in acute exacerbation of COPD: patient outcomes with amoxicillin vs. amoxicillin/clavulanic acid-data from 43,636 outpatients.

Kristian BaggePradeesh SivapalanJosefin EklöfFrederik Böetius HertzChristian Østergaard AndersenEjvind Frausing HansenJens Otto JarløvJens-Ulrik Stæhr Jensen

Published in: Respiratory research (2021)

In AECOPD, empirically adding clavulanic acid to amoxicillin is not associated with a better outcome; it seems safe for these patients to be treated with amoxicillin alone.

Keyphrases

chronic obstructive pulmonary disease
newly diagnosed
end stage renal disease
ejection fraction
liver failure
prognostic factors
respiratory failure
lung function
big data
intensive care unit
machine learning
drug induced
extracorporeal membrane oxygenation
acute respiratory distress syndrome
combination therapy