Involvement of tissue changes induced by neoadjuvant treatment in total mesorectal excision (TME): novel suggestions for determining TME quality.
Jin Cheon KimSeong Ho ParkJihun KimChan Wook KimIn Ja ParkYong Sik YoonJong Lyul LeeJong Hoon KimYong Sang HongTae Won KimPublished in: International journal of colorectal disease (2022)
NAT-associated tissue changes, somewhat interrupting complete TME, may provide unsolved clue to the relative inability of NAT to improve overall survival. The conventional three-tier grading of TME seems to be simplified into two tiers as complete and inappropriate.