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Melanoma arising in a patient with ataxia-telangiectasia: A call for full skin examinations in this patient population.

Sandra R OskaAllison ZarboDanielle YeagerBen J FriedmanTor A Shwayder
Published in: Pediatric dermatology (2020)
Ataxia-telangiectasia (A-T) is an autosomal recessive, multisystem disorder characterized by cerebellar ataxia and oculocutaneous telangiectasias that present in early childhood. Increased incidence of malignancy is also associated with A-T. Hematopoietic malignancies occur most commonly, with a majority being lymphoid cancers; however, there is a risk for other malignancies, such as breast, gastric, and other solid tumors. Herein, we report the case of a 28-year-old woman with A-T with melanoma.
Keyphrases
  • early onset
  • case report
  • risk factors
  • bone marrow
  • intellectual disability
  • skin cancer
  • autism spectrum disorder