Drug repurposing for COVID-19: current evidence from randomized controlled adaptive platform trials and living systematic reviews.
Yolanda AugustinHenry M StainesThirumalaisamy P VelavanAdeeba KamarulzamanPeter G KremsnerSanjeev Krishna
Published in: British medical bulletin (2023)
The timing of therapeutic interventions based on postulated mechanisms of action and the selection of clinically meaningful primary end points remain important considerations in the design and implementation of COVID-19 therapeutic trials.