Anticholinergic burden measures, symptoms, and fall-associated risk in older adults with polypharmacy: Development and validation of a prognostic model.

Truc Sophia DinhAndreas D MeidHenrik RudolfMaria-Sophie BrueckleAna I González-GonzálezVeronika BenchevaMatthias GogolinKym I E SnellPetra J M Elders Petra A ThuermannNorbert Donner-BanzhoffJeanet W BlomMarjan van den AkkerFerdinand M GerlachSebastian HarderUlrich ThiemPaul P GlasziouWalter Emil HaefeliChristiane Muth

Published in: PloS one (2023)

The ability of anticholinergic burden measures to predict falls does not appear to differ significantly, and the added value they contribute to risk classification in fall-prediction models is limited. Previous falls and dizziness / vertigo contributed most to model performance.

Keyphrases

community dwelling
machine learning
deep learning
physical activity
emergency department
middle aged
sleep quality