Enantioselective Intermolecular Heck and Reductive Heck Reactions of Aryl Triflates, Mesylates, and Tosylates Catalyzed by Nickel.
Xiaolei HuangShenghan TengYonggui Robin ChiWenqiang XuMaoping PuYun-Dong WuJianrong Steve ZhouPublished in: Angewandte Chemie (International ed. in English) (2020)
Nickel-catalyzed intermolecular Heck reaction of cycloalkenes proceeds well with aryl triflates, mesylates and tosylates in excellent enantiomeric ratios. The asymmetric reductive Heck reaction also works with a 2-cyclopentenone ketal, which is equivalent to conjugate arylation of the enone itself.