Circulating Tumor DNA in Stage III Colorectal Cancer, beyond Minimal Residual Disease Detection, toward Assessment of Adjuvant Therapy Efficacy and Clinical Behavior of Recurrences.

Tenna Vesterman HenriksenNoelia TarazonaAmanda FrydendahlThomas ReinertFrancisco Gimeno-ValienteJuan Antonio Carbonell-Asins Shruti Sharma Derrick RennerDina HafezDesamparados RodaMarisol Huerta Susana RosellóAnders Husted MadsenUffe Schou LøvePer Vadgaard AndersenOle Thorlacius-UssingLene Hjerrild Iversen Kåre Andersson GotschalckHimanshu SethiAlexey AleshinAndres CervantesClaus Lindbjerg Andersen

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Serial postoperative ctDNA analysis has a strong prognostic value and enables tumor growth rate assessment. The novel combination of ctDNA detection and growth rate assessment provides unique opportunities for guiding decision-making.

Keyphrases

circulating tumor
cell free
circulating tumor cells
decision making
patients undergoing
loop mediated isothermal amplification
real time pcr
label free
single molecule
data analysis