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Cabozantinib combination therapy for the treatment of solid tumors: a systematic review.

Daniel CastellanoAndrea B ApoloCamillo PortaJaume CapdevilaSantiago ViteriCristina Rodriguez-AntonaLidia MartinPablo M Rey
Published in: Therapeutic advances in medical oncology (2022)
This review demonstrates the promising efficacy outcomes of cabozantinib combined with other therapies, and a safety profile similar to cabozantinib alone. However, the findings are limited by the fact that most of the identified studies were reported as congress abstracts only. More evidence from randomized trials is needed to explore cabozantinib as a combination therapy further.
Keyphrases
  • combination therapy
  • metastatic renal cell carcinoma
  • metabolic syndrome
  • skeletal muscle
  • replacement therapy
  • glycemic control