Effects of Proton Pump Inhibitors on the Small Bowel and Stool Microbiomes.
Stacy WeitsmanShreya CellyGabriela LeiteRuchi MathurRashin SedighiGillian M BarlowWalter MoralesMaritza SanchezGonzalo ParodiMaria Jesus Villanueva-MillanAli RezaieMark PimentelPublished in: Digestive diseases and sciences (2021)
These findings suggest that PPI use is not associated with higher rates of SIBO. Relative abundance of Clostridiaceae was reduced in both the duodenal and stool microbiomes, and Streptococcaceae was increased in stool. The clinical implications of these findings are unknown.