E2F8 Induces Cell Proliferation and Invasion through the Epithelial-Mesenchymal Transition and Notch Signaling Pathways in Ovarian Cancer.

Kyung Jin Eoh Hee Jung KimJong Woo LeeLee Kyung KimSun-Ae ParkHyun-Soo KimYoung-Tae KimPeter J Koo

Published in: International journal of molecular sciences (2020)

Our findings indicate that E2F8 is highly correlated with ovarian cancer progression. Hence, E2F8 can be utilized as a prognostic marker and therapeutic target against ovarian malignancy.

Keyphrases

epithelial mesenchymal transition
signaling pathway
single cell
transforming growth factor
cell therapy
cell proliferation
induced apoptosis
oxidative stress
bone marrow
mesenchymal stem cells