How reliable is restaging MRI after neoadjuvant therapy in rectal cancer?

Rachel Gefen Zoe GaroufaliaNir HoreshMichael R FreundSameh Hany EmileAlbert ParladeMariana BerhoDaniela AllendeGiovanna Da Silva Steven D Wexner

Published in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2023)

We found low concordance levels between restaging MRI and pathology regarding TN stage and CRM status. Concordance levels were even lower for patients after TNT regimen and with a low rectal tumour. In the era of TNT and watch-and-wait approach, we should not rely solely on restaging MRI to make post-neoadjuvant treatment decisions.

Keyphrases

rectal cancer
locally advanced
contrast enhanced
magnetic resonance imaging
end stage renal disease
diffusion weighted imaging
ejection fraction
chronic kidney disease
lymph node
newly diagnosed
computed tomography
prognostic factors
mesenchymal stem cells
patient reported outcomes
cell therapy