CsHscB Derived from a Liver Fluke Clonorchis Sinensis Ameliorates Cholestatic Hepatic Fibrosis in a Mouse Model of Sclerosing Cholangitis.

Qian YuStephane KodaNa XuJing LiJian-Ling WangMan LiuJi-Xin LiuYu ZhangHui-Min YangBei-Bei ZhangXiang-Yang LiXiao-Cui LiRen-Xian TangKui-Yang ZhengChao Yan

Published in: Current molecular medicine (2023)

Overall, our data show that rCsHscB attenuates the progression of cholestatic fibrosis induced by DDC and supports the potential for manipulating the parasite-derived molecule to treat certain immune-mediated disorders.

Keyphrases

liver fibrosis
mouse model
liver injury
drug induced
electronic health record
big data
toxoplasma gondii
artificial intelligence
deep learning