Depression and risk of cognitive dysfunctions in amyotrophic lateral sclerosis.

Fabiola De MarchiMaria Francesca SarnelliValentina SolaraEnrica BersanoRoberto CantelloLetizia Mazzini

Published in: Acta neurologica Scandinavica (2019)

We reported a high prevalence of depression in the past in patients with ALS and cognitive impairment, as compared to patients without cognitive deficits, showing also that patients with both had a shorter survival time. These aspects require multidisciplinary approach at disease onset.

Keyphrases

cognitive impairment
end stage renal disease
depressive symptoms
ejection fraction
newly diagnosed
sleep quality
prognostic factors